Topic: experience-dependent valence

Object-directed behaviors are crucial for survival in natural environments. Although recent interest has focused on the encoding of objects and the representation of egocentric spatial relationships within the lateral entorhinal cortex (LEC), the downstream circuitry and mechanisms orchestrating these behaviors remain elusive. Similarly, significant progress has been made in uncovering amygdala circuit-level mechanisms for defensive and appetitive behaviors, yet integrating spatial object information within specific amygdala circuits remains a puzzle. To address these gaps, we unveil a com