Topic: explained variance

Replay of neuronal activity patterns during sharp-wave ripples (SPWr) is a crucial event for memory consolidation. Past events reactivation can be estimated by the explained variance (EV) between the pairwise neuronal correlations of consecutive behavioral episodes.We have investigated the physiological mechanisms of hippocampal reactivation in mice after the exploration of a linear maze. We found a strong reactivation during the subsequent SPWr events (EV=33.2±17.15%; n=19sessions), which did not correlate with changes in the average firing rate or the ripple rate of pyramidal neurons or inte