NeuID: A novel lncRNA exclusively expressed in the brain and controls neuronal function and identity
Ranjit Pradhan, M Sadman Sakib, Iga Grządzielewska, Eren Diniz, Dennis M. Krüger, Sophie Schröder, Susanne Burkhardt, Anna-Lena Schuetz, Farahnaz Sananbenesi, Andre Fischer · FENS Forum 2024
Non-coding RNAs are transcripts that do not encode proteins and comprise 98.5% of the human transcriptome. Among these, long non-coding RNAs (lncRNAs) have been implicated in various biological functions, including the control of gene expression and translation. The central nervous system (CNS) harbors a diverse array of lncRNA transcripts, yet the functions of many remain largely unexplored. In this study, we employed bulk and single-cell RNA sequencing approaches using human and mouse brain tissue to identify novel lncRNAs in both neuronal and non-neuronal cells, potentially associated with
ePoster · Neuroscience