Quantification of nonsense-free correlation uncovers the interaction between top-down and bottom-up sources of behavioral correlation in mouse V1
Peijia Yu, Ha Yun Anna Yoon, Yuhan Yang, Yunlong Xu, Olivia Gozel, Na Ji, Brent Doiron · COSYNE 2025
Brain-wide neuromodulation by behavioral variables, such as locomotion, pupil area, and face motion, have been observed in mice (Stringer et al., 2019; Musall et al., 2019). To study this mechanism at higher spatial resolution, we used two-photon imaging that allows recording of individual neuronal and synaptic bouton activity in mouse primary visual cortex (V1), while the animal's face was simultaneously videotaped. We aim to understand how face motion is related to the population activity of both cortical neurons and their lateral geniculate nucleus (LGN) afferents, during both visual stimul
ePoster · Neuroscience