Topic: fear memory retention

Exposure-based therapies can be highly effective for patients with post-traumatic stress disorder (PTSD) but up to one third of patients do not respond adequately. Repeated exposure to fear-evoking cues is hypothesized to suppress fear responses through the acquisition and recall of new safety learning in a process termed fear extinction. Transcranial direct current stimulation (tDCS) has gained interest as a non-invasive neuromodulation technique that may suppress fear expression or augment fear extinction. We previously established that in mice, repeated anodal tDCS applied over the prefront