Topic: flexible coding

The Orbitofrontal Cortex (OFC) is critical for flexible coding and updating of stimulus value which in turn explains its role in decision making processes. Lesion studies and physiological recordings in experimental rodents are in line with subarea specific functional differences, partly comparable to previous primate studies. Emotionally relevant inputs from dopaminergic reward centers and amygdala during strong emotional reactions are also crucial in this regard. In order to explain the distinctive role of each of the OFC subregions, it is important to study the anatomical input-output archi