Topic: fluorescence-activated cell sorting

Alcohol-associated memories play an important role in relapse in alcohol use disorder. Disrupting these memories, which become labile upon retrieval, through interference with their reconsolidation process, could reduce relapse. Memories are thought to be encoded within specific patterns of sparsely distributed neurons, called neuronal ensembles. Here, we explored the role of neuronal ensembles in alcohol-memory reconsolidation and relapse and characterized their transcriptional signature. Upon retrieving alcohol-related memories, we observed increased neuronal activation in the nucleus accumb

Photoreceptors, the light sensors of the retina, come in two varieties: the light-sensitive rod photoreceptors, which are responsible for night vision, and the cone photoreceptors, which operate at higher light intensities and are responsible for daylight and color vision. These different tasks require specific morphological and molecular adaptations of rod and cone photoreceptors in the processes of transduction and transmission of light signals. Here we present the first deep proteome resource of mouse rod and cone photoreceptors to our knowledge. We have established a method using fluoresce