Prefrontal cortex alterations underlying attentional modulation of sensory information in the Fmr1KO mouse model of autism spectrum disorder
Maria Gueidão Costa, Awen Louboutin, Ourania Semelidou, Roman Böhringer, Ignacio J. Marín Blasco, Andreas Frick, Olga Peñagarikano, Melanie Ginger · FENS Forum 2024
Atypical sensory processing affects approximately 90% of individuals with autism spectrum disorder (ASD) and has been recently considered a core ASD symptom. In accordance with neurophysiological findings in human subjects, preclinical studies have found altered activity of primary sensory neocortices and sensory association areas following sensory stimuli and perceptual paradigms in several genetic mouse models of ASD. Attention deficits are a common comorbidity of autism and may impact other symptoms. Indeed, recent research suggests that alterations in attention and sensory processing are i
ePoster · Neuroscience