Cortical inhibitory tuning reflects the Fourier components of locally encoded features
Adrian Duszkiewicz,Sofia Skromne Carrasco,Pierre Orhan,Eliott Owczarek,Eleonor Brown,Emma Wood,Adrien Peyrache · COSYNE 2022
Inhibition plays an important role in shaping neural representations. Still, it is unclear whether inhibitory neurons merely refine the tuning of excitatory (EX) neurons or encode a parallel neural representation. We aimed to uncover the principles of inhibitory tuning in the cortex, using a simple system encoding a 1-dimensional sensory signal - the head-direction (HD) system. To this end, we recorded populations of neurons in the postsubiculum (PoSub), the primary cortical hub of the HD system. While excitatory HD cells had narrow receptive fields, fast-spiking (FS) interneurons had broad an
Sat, Mar 19, 2022