Assessment of task-specific glucose metabolism with non-invasive functional PET
Godber Mathis Godbersen, Pia Falb, Sebastian Klug, Leo R. Silberbauer, Murray Bruce Reed, Lukas Nics, Marcus Hacker, Rupert Lanzenberger, Andreas Hahn · FENS Forum 2024
Functional positron emission tomography (fPET) imaging using [18F]FDG serves as an index of neuronal activity independent of neurovascular coupling (Villien 2014). However, its absolute quantification through arterial blood sampling requires substantial resources (Hahn 2016). We investigate whether task-specific metabolism can be assessed without blood sampling.52 healthy subjects (23.2 ± 3.3 years, 24 female) performed Tetris® during an [18F]FDG fPET scan. Data acquisition, processing and analysis was performed as in (Hahn 2020). The general linear model (GLM) was used to identify task-specif
ePoster · Neuroscience