Topic: GABA-mediated inhibition

Amacrine cells, which are pivotal interneurons in the retina, influence stimulus processing by modulating synapses between bipolar and ganglion cells, which form the retinal output. However, understanding their specific roles is challenging because of the diversity of amacrine cell types (60 in total), making analysis difficult using conventional methods. This study aims to investigate the role of two novel amacrine cells in retinal processing using an innovative approach. By expressing optogenetics with specific promoters (ProB13 and ProD20), we use single-cell 2-photon holographic stimulatio