Investigation and modulation of cortical excitability in awake rhesus macaques with non-invasive transcranial magnetic stimulation and electroencephalography
Anna Padanyi, Balázs Knakker, Evelin Kiefer, Szuhád Khalil, Antonietta Vitális-Kovács, Rafaella Riszt, Judit Zubánné Inkeller, István Hernádi · FENS Forum 2024
Disruption in the excitatory and inhibitory (E/I) balance of cortical networks is well-characterised in age-related neurocognitive disorders (NCD), impacting functional cognitive decline. Thus, utilising non-invasive transcranial magnetic stimulation (TMS) and electroencephalography (EEG) methods, similarly applicable in both patients and translationally relevant preclinical animal models, we established baseline cortical excitability in rhesus macaques, followed by modulation of the E/I balance by diazepam (GABAA PAM).We recorded scalp-EEG from 27 electrodes by a telemetric amplifier system d
ePoster · Neuroscience