Topic: GABAergic activity

Excitatory and Inhibitory indexes measured by Transcranial Magnetic Stimulation (TMS) allow the investigation of neuronal transmission and plasticity of the primary motor cortex (M1). Various forms of local GABAergic activity in the human M1 can be examined using paired-pulse paradigms (Sasaki et al., 2021). Intracortical facilitation (ICF), a glutamate-mediated excitatory index, is contrasted with short-interval intracortical inhibition (SICI), an inhibitory index dependent on the GABAergic system (Rotenberg et al., 2014). Mirror neurons, which fire both during action observation and executio