Mapping the projections of serotonergic dorsal raphe neurons in zebrafish
Lucía Jiménez Fernández, Florence Kermen · FENS Forum 2024
The dorsal raphe nucleus (DRN) contains the largest population of serotonergic (5-HT) neurons in the central nervous system. The DRN modulates a wide range of physiological functions and brain states, mostly due to its widespread and heterogeneous projections. Evidence suggests that the DRN comprises different sub-systems with distinct neurotransmitter phenotype, connectivity and function. These sub-systems are difficult to characterize in the complex mammalian DRN. To overcome this, we address these questions in zebrafish larvae, leveraging their simpler and conserved DRN.Here, we establish a
ePoster · Neuroscience