Topic: gait cycle

Climbing fiber inputs to the cerebellar cortex drive low-frequency bursts of activity in Purkinje cells - known as complex spikes - which are thought to encode sensorimotor errors critical for movement refinement. Yet, the precise nature of these signals remains elusive for complex behaviors requiring the coordination of multiple body parts, such as locomotion. To understand the contribution of olivary inputs to the cerebellar cortex in locomotor coordination, we performed calcium imaging from Purkinje cell dendrites in unrestrained mice running on treadmills. Combining miniscope imaging with