Topic: gamma-based biomarkers

Gamma oscillations are believed to arise from the interaction between excitation and inhibition (E-I) in the neural circuitry. However, the dependency of gamma power on E-I interaction is not well characterized. Increasing the drift-rate of the visual grating, which changes E-I balance, increases the peak frequency of gamma while power initially increases and later attenuates. Importantly, this power versus drift-rate tuning curve is altered for subjects with autism or premenstrual dysphoric disorder. A recent MEG study in humans (Orekhova et al., 2020) examined the combined effect of contrast