Sequential appetite suppression by oral and visceral feedback to the brainstem
Truong Ly, Jun-Yop Oh, Nilla Sivakumar, Sarah Shehata, Naymalis La Santa Medina, Heidi Huang, Zhengya Liu, Wendy Fang, Chris Barnes, Naz Dundar, Brooke Jarvie, Anagh Ravi, Olivia Barnhill, Chelsea Li, Grace Lee, Jaewon Choi, Heeun Jang, Zachary Knight · FENS Forum 2024
The termination of a meal is controlled by dedicated neural circuits in the caudal brainstem. A key challenge is to understand how these circuits transform the sensory signals generated during feeding into dynamic control of behaviour. The caudal nucleus of the solitary tract (cNTS) is the first site in the brain where many meal-related signals are sensed and integrated, but how the cNTS processes ingestive feedback during behaviour is unknown. Here we describe how prolactin-releasing hormone (PRLH) and GCG neurons, two principal cNTS cell types that promote non-aversive satiety, are regulated
ePoster · Neuroscience