Anatomo-functional diversity of medullary V2a neurons for limb and cranial nerve-mediated movements
Alexis d'Humières, Mathilde Gonin, Guillaume Le Goc, Giovanni Usseglio, Edwin Gatier, Julien Bouvier · FENS Forum 2024
The brainstem reticular formation (RF) is key for controlling movements, both at the spinal (e.g., trunk, limbs) and at supra-spinal (e.g., orofacial, ocular) levels. Yet, in this heterogenous structure, the specific contributions of discrete cellular populations to identified unitary actions remain poorly understood. The V2a identity (Chx10-expressing) circumscribes a subgroup of glutamatergic neurons along the rostrocaudal axis of the pontomedullary RF. In the mouse, those located in the gigantocellular reticular nucleus (GRN) were shown to control limb and head-related motor components of o
ePoster · Neuroscience