Specialized corticothalamic connections between the layer 5 of the frontal cortex and the thalamus
Hajnalka Bokor, Nóra Hádinger, Boglárka Tóth, Naoki Yamawaki, Gordon Shepherd, Judit Makara, László Acsády · FENS Forum 2024
Top-down corticothalamic layer 5 afferents (L5) have profound impact on the activity of their thalamic targets. However, L5 afferents were mainly studied in sensory corticothalamic circuits. In this project we asked whether the characteristics of L5 corticothalamic inputs in sensory and frontal cortical regions have similar properties. We found that L5-thalamus pathways display regional specificity. Sensory L5-thalamic axons establish giant terminals, as described, but the frontal L5-thalamic boutons are small, their size distribution is closer to that of the L6 boutons. Small L5 terminals are
ePoster · Neuroscience