Functional expression of inhibitory glycinergic neurotransmission onto somatostatin positive neurons in the ventral pallidum
Alejandro Alcaino, Chiayu Chiu, Andrés Chávez · FENS Forum 2024
Although traditionally thought to act primarily in the spinal cord, emerging evidence support important inhibitory functions by glycinergic transmission in the brain. In the ventral pallidum (VP), glycinergic afferents from the brainstem make synapses onto cholinergic interneurons to regulate arousal. Notably, VP is comprised of a heterogeneous population of GABAergic neurons, of which those that express somatostatin (SOM+) comprise a significant group and have been implicated in the control of sleep and wakefulness directly inhibiting cholinergic, glutamatergic and parvalbumin neurons. Here,
ePoster · Neuroscience