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Topic: Golgi cells

Seminar
1 seminar

In Biology and Neuroanatomy

Seminar · Neuroscience

Recurrent problems in spinal-cord and cerebellar circuits

Steve Edgley · Department of Physiology, Development and Neuroscience, University of Cambridge

Tue, Feb 16, 2021 · 13:00 UTC

One of the best established recurrent inhibitory pathways is the recurrent inhibition of mammalian motoneurons through Renshaw cells. Golgi cells form an inhibitory feedback circuit in the granular layer of cerebellum. Feedback inhibitory pathways are long established “textbook” elements of neural circuitry, but in both cases their functional role has not been well established. Here I will present some new observations on the function of recurrent inhibition in the spinal-cord, supporting the idea that this connection frequency tunes transmission of inputs through motoneurons. Secondly, I will