Clinical grade production of large-scale neural progenitor cells (NPC) for Huntington’s disease treatment
Josep M. Canals, Marc Estarellas, Georgina Bombau, Maria Camanyes, Irene Porcar, Jordi Abante, Unai Perpiña · FENS Forum 2024
Regenerative medicine aims to revolutionize medical practice by offering cures for severe diseases. This is achieved through the utilization of human pluripotent stem cell (hPSC) lines, which undergo controlled differentiation before being transplanted into patients. A significant challenge lies in developing safe, robust, and controlled differentiation protocols, requiring the adaptation of research-only reagents to good manufacturing practice (GMP) standards.Cell-based therapies for Huntington’s disease aspire to restore neuronal circuitry and function by replacing lost neurons. Here, we pre
ePoster · Neuroscience