Topic: granular retrosplenial cortex

Efficient spatial navigation in complex environments relies on the construction of an egocentric cognitive map. Recent studies have reported that subpopulations of excitatory neurons in the granular retrosplenial cortex (RSC) are selectively activated at specific distances and orientations relative to environmental boundaries and vertices, tuned by the heading directions of the animal, to perform egocentric vector coding of the environmental geometry. However, the neural circuit mechanisms explaining how egocentric representation of vertices and boundaries emerges are yet unknown. One possible