Hippocampal activation induced by voluntary apnea in rats
Simon Désiré Guedang Nyayi, Jorelle Linda Damo Kamda, Laetitia Chambrun, Roseline Poirier, Heather McLean, Marion Noulhiane, Valérie Doyère, Harquin Simplice Foyet · FENS Forum 2024
The oxidative stress and inflammation provoked by hypoxia can lead to damage to neurons in the hippocampus, a structure that plays a key role in learning and memory processes. Prevention of hypoxia-related damages may be achieved through different means: pharmacologically or behaviorally. Some plants have strong antioxidants properties, such as Guiera senegalensis (GS). Alternatively, performance of free-divers, without memory loss, suggests neuroprotective effects of extended training to apnea. We developed a rat model of hypoxia under voluntary apnea. Training consists of 3 to 4 weeks of hab
ePoster · Neuroscience