Topic: hand velocity

Substantial progress towards understanding neural computation has been made by studying the dynamical systems that govern neural population activity. Because dynamical models make predictions about the temporal evolution of neural states, perturbations of neural activity are a powerful tool to evaluate and refine these models. Here, using electrodes and Neuropixels in the motor cortices of macaques engaged in a reaching task, we probed how local population dynamics are affected by two perturbation modalities: optogenetic excitation and electrical intracortical microstimulation (ICMS). Both st