Constructing an artificial intelligence algorithm based on awake mouse brain calcium imaging as a rapid screening platform for the development of Parkinson's disease drugs
Shiu-Hwa Yeh, Tung Chun-Wei · FENS Forum 2024
The traditional method in the development of drugs for neurodegenerative diseases, such as Alzheimer's or Parkinson's disease, necessitates the use of various animal models to assess complex behavioral changes. This process is not only time-consuming but also prone to misjudgments due to interspecies behavioral differences. In contrast, neural activity data gathered by head-mounted microscopy platforms represent integrated information that is relatively straightforward to interpret and exhibits low variability between species. This makes it an excellent resource for the development of correspo
ePoster · Neuroscience