Topic: heading representations

Spatial cognition depends on an accurate representation of orientation within an environment. Head direction cells in distributed brain regions receive a range of sensory inputs, including proprioceptive, vestibular, and somatosensory information, but visual input is particularly important for aligning their responses to environmental landmarks. To investigate how population-level heading responses are aligned to visual input, we recorded from the retrosplenial cortex (RSC) of head-fixed mice in a moving environment using two-photon calcium imaging. RSC receives strong inputs from both visual