Topic: hemiparkinsonian rats

The expression of the transmembrane neuronal gap junction protein connexin 36 (Cx36) was investigated in the reticulo-thalamic nucleus (RT) and in the CA3 region of hippocampus in a rat model of Parkinson’s disease (PD). We compared the Cx36 expression in a rat model of PD (the hemiparkinsonian rats with PD cholinopathy - unilateral lesion of the substantia nigra pars compacta (SNpc) with bilateral lesion of the pedunculopontine nucleus (PPT)) versus control rats.A total of 12 adult male Wistar rats were divided in control group (n = 6) and PD group (n = 6). We performed a fluorescence immunoh