The hypoxia-inducible factor 1alpha and primary cilia – a functional analysis of the interplay in neuronal cells
Pascal Schneider, Tristan Leu, Joachim Fandrey · FENS Forum 2024
Primary cilia, also called "the cells antenna", are centriole based sensory cellular organelles, which are present on almost all mammalian cells and became important during the last decades. They realize a variety of functions, including maintaining neuroplasticity and the adaption to hypoxic conditions via a variety of signalling pathways, including the SHH-signalling, the MEK-ERK-signalling or the PDGFRa-signalling pathway. Based on these observations, the work pursued the goal to investigate the interplay of the hypoxia-inducible factor 1alpha and primary cilia in neuronal cells. The establ
ePoster · Neuroscience