Topic: High-risk research

Grant
6 grants
Grant

Transformative sustainable AI technologies

UK Research and Innovation
Nov 10, 2026

UK Research and Innovation is funding speculative, high-risk projects that could deliver a step change in the sustainability of future AI systems. Proposals may address energy-efficient algorithms, resource-constrained AI, hardware-software co-design, repairable hardware, and other technology-led advances across the AI stack.

Grant

Next generation artificial intelligence: explainable AI

UK Research and Innovation
Oct 20, 2026

UKRI and EPSRC are funding speculative, high-risk fundamental research with the potential to produce a step change in the explainability of future AI systems. The call welcomes work on mechanistic interpretability, output reasoning, process examination, imposed explainability, uncertainty quantification, and novel approaches beyond those examples.

Grant

NIH Director’s Transformative Research Award (R01 Clinical Trial Optional)

NIH Common Fund
Sep 3, 2026

The NIH Common Fund supports individuals or teams pursuing exceptionally innovative, unconventional research with the potential to create or overturn major paradigms across biomedical and behavioral science.

Grant

NIH Director’s New Innovator Award Program (DP2 Clinical Trial Optional)

National Institutes of Health
Aug 17, 2026

The NIH Common Fund supports exceptionally creative early-stage investigators pursuing bold, high-impact biomedical or behavioral research without requiring preliminary data.

Grant

Targeted Grants in MPS

Simons Foundation

Supports high-risk projects of exceptional promise and scientific importance in mathematics and the physical sciences, with funding for up to five years; letters of intent are accepted on a rolling basis and there is no recommended or assumed funding level.

Grant

New Ideas - Request for Applications

Simons Foundation Autism Research Initiative

The Simons Foundation Autism Research Initiative supports bold, high-risk, high-reward ideas that could open new directions in autism science. Letters of intent are accepted on a rolling basis, with selected applicants invited to submit a full application for projects lasting up to two years.

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