Topic: Hilar-perforant-path-associated interneurons

The hippocampus plays a pivotal role in the formation of episodic memories, facilitating spatial navigation and detection of novel stimuli. Within this structure, the dentate gyrus (DG) is crucial for discriminating novel from familiar content. Despite GABAergic inhibitory interneurons (INs) being increasingly recognized to participate to the hippocampal computation by controlling the activity of principal cells, the specific mechanisms by which they contribute to the encoding of episodic memories remain elusive. This study explores how interneurons (INs) representations of spatial context are