Topic: hindlimb movements

Voluntary movement in animal is regulated be the sensorimotor cortex. The cortex generates the motor command as well as signals to increase the weight of relevant sensory information (sensory gating) that are both essential for the realization of adapted and coordinated movements. The corticospinal tract (CST) is the most direct pathway conveying these signals. Our previous work on anesthetized mice has shown that the lumbar projecting CST induces mainly the modulation of sensory information rather than the direct control of muscle contraction. The aim of our study is to identify the implicati