Topic: hippocampal CA1 place cells

The hippocampus and entorhinal cortex form an “information loop”: The superficial layers of the entorhinal cortex provide the majority of excitatory input to the dorsal hippocampus, whereas the deep layers of the entorhinal cortex receive most of their input from the hippocampus. The medial entorhinal cortex (MEC) is crucial for the formation of spatial memory, and its inactivation impairs both recent and remote memory retrieval during spatial navigation tasks- indicating a key role for entorhinal neural codes in long term memory. Recent studies have found that hippocampal place codes graduall