Topic: hippocampal ensembles

Memories encoded during infancy are often rapidly forgotten. This accelerated memory decline is known as infantile amnesia, and is hallmarked by the inability of natural cues to induce the retrieval of early-life memories later in life. Remarkably, infant memories in rodents are not lost. Artificial stimulation of infant memory ensembles can drive according behavior, leading to the hypothesis that infant memories persist through time albeit in a latent state. In our study, we aim to unravel under which circumstances “forgotten” infant memory ensembles can be reactivated by natural cues in adul