Topic: hippocampal pattern separation

Humans have a remarkable ability to remember whether they've seen an image before, with considerable visual detail. Unlike the visual perceptual confusions of images, visual memory confusions are not approximately predicted by the distances between population representations in inferotemporal cortex (ITC), or its analogs in artificial neural networks. The leading hypothesis to account for this discrepancy proposes that the hippocampus (HC) applies a nonlinear transformation of its cortical inputs to better separate them before memory storage, a mechanism called hippocampal pattern separation (