ePoster · Computational Neuroscience
An inhibitory network model explains the transient dynamics of hippocampal ripple oscillations
Natalie Schieferstein,Tilo Schwalger,Richard Kempter,Benjamin Lindner · COSYNE 2022
Thu, Mar 17, 2022
Hippocampal ripple oscillations (140–220 Hz) have been implicated in important cognitive functions such as memory consolidation (Buzsáki 1989). Their generating mechanism however remains unclear, although various models have been proposed. We suggest that transient features of ripples can guide model selection: So far only the “bifurcation-based” inhibitory network model (Donoso et al. 2018, Brunel and Hakim 1999) could reproduce the experimentally observed intra-ripple frequency accommodation (IFA) — an asymmetry in the instantaneous ripple frequency in response to transient, sharp wave-like