The importance of housing conditions in implementing the sex as a biological variable (SABV) policy in neuroscience rodent research
Ivana Jaric, Océane La Loggia, Jovana Malikovic, Marc W Schmid, Janja Novak, Bernhard Voelkl, Irmgard Amrein, Hanno Würbel · FENS Forum 2024
Neuroscience research has historically exhibited bias towards male subjects, resulting in limited representation of females in preclinical studies. Despite recent policies emphasizing equal sex representation, questions persist regarding optimal housing practices for male and female animals in research facilities. We aimed to investigate the effects of housing male and female mice with (mixed-sex housing room) or without (same-sex housing room) odor cues from conspecifics on behavior, hippocampal structure, molecular plasticity, and sex-dependent biological function. To do so, we housed two in
ePoster · Neuroscience