Topic: histidine decarboxylase-positive neurons

How is the retinal visual processing affected by the behavior and internal states of an animal? The structure and function of the vertebrate retina have been extensively studied ex vivo across species. Recent studies, however, demonstrated that the retina operates differently in vivo, especially in an awake condition. Using in vivo recording methods in mice together with chemogenetic tools, here we identified the effects of the histaminergic system on retinal visual responses in the context of the circadian rhythm. Specifically, we found histaminergic modulation of the retinal response kinetic