Post-transcriptional regulation of neurodevelopment mediated by extracellular vesicles
Barbara Oliveira, Satish Arcot Jayaram, Walter Kaufmann, Armel Nicolas, Daniel Malzl, Jeorg Menche, Gaia Novarino · FENS Forum 2024
The biological potential of extracellular vesicles (EVs) arises from their ability to transport and deliver cargo within and across cells. While widely accepted as a cell-cell communication vehicle, the dynamic range of these vesicles during brain development remains largely unexplored. Knowing this, we aimed to identify novel avenues of cellular communication and unravel the contribution of EV cargo to brain development. Leveraging a multi-omics approach, we profiled the miRNA, RNA, and proteomic contents of EVs spanning embryonic to juvenile states of mouse brain development. With this appro
ePoster · Neuroscience