Rostrocaudal spinal cord patterning during the swim-to-limb transition of Xenopus metamorphosis
Stavros Papadopoulos, Clara Becker, Florina Alexandra Toma, Johanna Sonntag, Lora Beatrice Sweeney · FENS Forum 2024
As tadpoles switch from undulatory to ambulatory locomotion a repeated array of axial swim units transitions to a limb-torso-limb architecture along the rostrocaudal axis. Exemplifying this, at early tadpole swim stages, motor neurons of a single type are evenly distributed along the spinal cord. While, at later frog stages, level-specific motor columns are added at both thoracic and limb levels. Here, we show rostrocaudal differences in inhibitory and excitatory interneuron populations emerge during frog metamorphosis. This raises the question of when differences in neuronal architecture dev
ePoster · Neuroscience