The role of TRH neurons in energy homeostasis and regulation of brown adipose tissue
Andreea Constantinescu, Luca Höhne, Jens Mittag, Markus Schwaninger, Helge Müller-Fielitz · FENS Forum 2024
Thermogenesis is a vital physiological process that contributes to maintaining energy homeostasis, metabolic health, and adaptation to environmental changes. Central for metabolic regulation is the hypothalamus, orchestrating a diverse array of neuroendocrine systems. Within this intricate network, the role of thyrotropin-releasing hormone (TRH) neurons of the hypothalamus is unknown. Our project aimed to delineate TRH populations implicated in modulating brown adipose tissue (BAT)-derived thermogenesis. Employing an exploratory approach utilizing retrograde tracers from BAT, we pinpointed thr
ePoster · Neuroscience