Topic: Human adipose-derived stem cells

The primary and progressive degeneration of motor system is the main pathogenic process that characterizes amyotrophic lateral sclerosis (ALS), which is a fatal neurodegenerative disease of motor neurons (MN) in the primary motor cortex and spinal cord. Patients’ death occurs in 3–5 years after the diagnosis due to the progressive palsy and dysfunction of the respiratory system. The etiology is known in most of the patients with the most frequent sporadic ALS (90%), and clinical onset and symptoms are highly heterogeneous. Irrespective of the cause and initial onset the ALS is an almost select