Topic: human brain gene expression

Computational methods emerged as novel tools in the quest for our human origins (Piszczek et al., 2024). Fusing archaic genomes, human brain gene expression data, and fMRI allowed to extrapolate multi-genic selection during the 60 Mya of Anatomically Modern Humans (AMH) ancestral evolution (Kaczanowska et al., 2022). This approach reconstructed traces of adaptive selection across cognitive traits, offering a comprehensive perspective on evolutionary pressures shaping diverse cognitive functions. Here, we build on this workflow to specifically target and expand on the evolution of socio-affecti