Topic: human cortical astrocytes

Astrocytes play a fundamental role in numerous neural processes. In this study, we present preliminary data from ex vivo human cortical astrocytes obtained from Temporal lobe resections for epilepsy treatment and examined using whole cell patch clamp and 2-photon imaging techniques. Calcium (Ca2+) imaging reveals that these astrocytes exhibit a high frequency of Ca2+ transients in their fine processes compared to whole-cell responses, a finding consistent with astrocyte activity recorded in rodents. While the morphology of human astrocytes bore similarities to their rodent counterparts, they d