Topic: human fetal retinas

Aim: The molecular mechanisms involved in the development and specification of the retinal ganglion cell (RGC) types have been studied thoroughly in animal models, especially mice. In comparison, human RGCs are much less studied. Our aim was to characterize human RGCs anatomy and molecular markers expression at different fetal life stages in comparison to their mouse orthologues. Methods: The study was conducted on human fetal retinas collected from therapeutic abortion specimens under written informed consent and on C57B6/J mouse retinas. Immunofluorescence staining was performed on vertical