Topic: human memory encoding

The electrophysiological mechanisms of human memory encoding and recall are incompletely understood. Precise interaction of single-neuron activity and brain oscillations presumably play a critical role in this process. Here, we used human single-neuron recordings from an object-location memory task with separate periods for encoding and retrieval to analyze the timing of single-neuron activity in the medial temporal lobe relative to the local theta rhythm. 18 epilepsy patients participated in the task and contributed to 27 experimental sessions. We extracted single-neuron action potentials fro