Topic: human sympathetic neurons

The peripheral nervous system (PNS) influences the function of nearly all tissues in the body, regulating various physiological processes. When compared to the central nervous system (CNS) type of neurons, an equivalent understanding of the functional properties of human PNS neurons is lacking in vitro while there is a need for better characterization of electrophysiologically mature human PNS neurons. Generating subtypes of human PNS neurons opens possibilities for physiologically more relevant innervation and OoC models both in health and disease.Here, we modified existing differentiation pr