ePoster · Neuroscience
Neurotoxin mediated neuronal dysfunction regulated by lysosomal function
Jinhong Wie · FENS Forum 2024
Neurotoxins are numerous groups of drugs that lead detrimental effects on the neuronal system and caused the cognitive and neurological impairments. Intracellular signaling and homeostasis can disturb by those toxins. Lysosomes are crucial organelles to digest waste disposal and supply the essential materials. It is still unknown to connection between lysosomal homeostasis and neurological dysfunction. Here, we investigated how to attenuate the neurodegeneration though managing lysosomal function. After treatment of hydroperoxide as known as one of the neurotoxins, N2A cell proliferation decre