Topic: hypoperfusion

Spreading Depolarizations (SDs) are electrographic events that arise post-stroke and correlate with worsening outcome. The haemodynamic response to SD is vasodilation in well perfused tissue. However, SDs induce hypoperfusion in ischemic tissue, further decreasing the viability of ‘at risk’ tissue.Traditional metal-based electrodes are limited in their ability to faithfully record DC-coupled potential shifts including SD. In contrast, Graphene micro-transistor arrays (gSGFETs) precisely record SDs without signal attenuation, distortion or voltage drift; and their transparency allows simultaneo