Involvement of the hypothalamic A11 nucleus in the pathophysiology of Parkinsonian-like nociceptive disabilities
Alexia Duveau, Rabia Bouali-Benazzouz, Frederic Naudet, Juliane Bonneau, Pascal Fossat, Abdelhamid Benazzouz · FENS Forum 2024
Parkinson’s disease (PD) is a neurological and neurodegenerative disease characterized by themanifestation of motor and non-motor symptoms. Among these, pain is one of the most frequent,affecting around 85% of patients and contributing to a deterioration in their quality of life.Nowadays, pain treatment in PD is still inefficient due to the lack of knowledge of the underlyingmechanisms. However, we know that pain can be modulated by the monoaminergic descendingpathways projecting to the dorsal horn of the spinal cord (DHSC). Thus, the aim of the present studyis to unravel the involvement of th
ePoster · Neuroscience